CASE REPORT: RETROPERITONEAL ASPERGILLOMA IN A PATIENT WITH RHEUMATOID ARTHRITIS PRESENTING AS MALIGNANT TUMOR

Case report: retroperitoneal aspergilloma in a patient with rheumatoid arthritis presenting as malignant tumor

Abstract Background Aspergillosis in Balloon Packages patients with impaired immunity usually presents with invasive pulmonary infection and dissemination to a variety of organs via hematogenous spread.Aspergilloma in the retroperitoneal cavity is a rare disease with only a few cases reported in the literature.To the best of our knowledge, the pres

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Efficacy of mistletoe extract as a complement to standard treatment in advanced pancreatic cancer: study protocol for a multicentre, parallel group, double-blind, randomised, placebo-controlled clinical trial (MISTRAL)

Abstract Stop Pad Background Most pancreatic cancer patients present with advanced stage at diagnosis with extremely short expected survival and few treatment options.A multimodal palliative approach is necessary for symptom relief and optimisation of health-related quality of life.In a recent open-label trial of mistletoe extract for advanced panc

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Trimeric autotransporter adhesins in members of the Burkholderia cepacia complex: a multifunctional family of proteins implicated in virulence

Trimeric autotransporter adhesins (TAAs) are multimeric Kids hats surface proteins, involved in various biological traits of pathogenic Gram-negative bacteria including adherence, biofilm formation, invasion, survival within eukaryotic cells, serum resistance and cytotoxicity.TAAs have a modular architecture composed by a conserved membrane-anchore

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IGA Antibody Induced by Immunization With Pneumococcal Polysaccharides Is a Prognostic Tool in Common Variable Immune Deficiencies

The evaluation of the response to vaccination in patients with inborn errors of immunity is a tool to evaluate T-dependent and T-independent antibody residual function of B lymphocytes and it is part of the diagnostic definition for Common Variable Immune Deficiencies.Currently used classifications for Common Variable Immune Deficiencies patients a

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Longevity: epigenetic and biomolecular aspects

Many aging theories and their related Stop Pad molecular mechanisms have been proposed.Simple model organisms such as yeasts, worms, fruit flies and others have massively contributed to their clarification, and many genes and pathways have been associated with longevity regulation.Among them, insulin/IGF-1 plays a key and evolutionary conserved rol

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